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In addition, a 2019 study published in JAMA Network Open suggests that post-menopausal women who habitually take high doses of vitamin B12, especially if they're also taking high doses of vitamin B6, are at higher risk of hip fracture

doi: 10.1016/j.molimm.2025.04.015 34 Samyuktha AarthiSPandiarDSubramanianRKrishnanRP

doi: 10.1038/sj.ejcn.1602594

That does not sound like much until you consider that losing 10 pounds of lean mass, which is entirely possible on GLP-1 medications without strength training, could reduce your daily calorie burn by 60-100 calories permanently